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LAM/TSC Seminar Series

The VHL Tumor Suppressor Protein: Cancer and Oxygen Sensing

June 5, 2008

Speaker: William Kaelin, MD (DFCI/HMS)

Dr. William Kaelin is currently a Professor of Medicine at Dana Farber Cancer Institute and Harvard Medical School, and a Senior Physician at Brigham and Women's Hospital. He obtained an MD from Duke University Medical School in 1982. His laboratory studies tumor suppressor genes and the normal functions of the proteins they encode. The long-term goal of his work is to lay the foundation for the development of new anticancer therapies based on the functions of specific tumor suppressor proteins. His laboratory is currently concentrating on the von Hippel-Lindau tumor suppressor protein (pVHL), the retinoblastoma tumor suppressor protein (pRB), and the p53-like protein p73.

Discussant: Leif Ellisen, MD, PhD (MGH Cancer Center/HMS)

Dr. Leif Ellisen is currently an Associate Professor of Medicine at Harvard Medical School and an Associate Physician at MGH Cancer Center at Massachusetts General Hospital.